Job Description:

We are seeking a highly motivated and collaborative technical leader responsible for innovation and development of our LNP platform technology. The successful candidate will work within a cross-functional teams to design and develop LNPs/tLNP platform technology in support of our pipeline. The candidate is responsible for establishing and leading LNP innovation strategy with respect to lipid design, chemistry, formulations and targeted non-viral delivery systems with line of sight to future products and pipeline growth

Responsibilities and Duties:

Serves as a scientific and technical leader in the organization with special emphasis on lipid nanoparticle (LNP)-based drug delivery systems for nucleic acids.
Lead the strategy to innovate, develop, and optimize the targeted LNP platform to support programs across therapeutic areas
Have a deep understanding of lipid and LNP design principles, stability, scale-up and scale out processes and their impact on critical product attributes. Ensure successful scale up of drug product formulation production and purification unit operations from bench scale to larger scale in support of a development candidate.
Prepare LNP-related project plans, timelines, budget projections, and ensure development activities proceed in alignment with key stakeholders in alignment with organizational goals and budget
Lead analysis and summarization of complex data sets, and communicate clearly at internal program meetings, cross-functional reviews and governance forums.
Collaborate with various discovery and development groups across the organization including mRNA, antibody, analytical and process development groups to advance pipeline programs
Lead authoring, review and approval of technical reports relevant to the function
Manage and mentor a team of >10 scientists and associates at AbbVie sites located on the east and west coasts

Qualifications

PhD. in Chemistry, Biochemistry, Chemical or Bioengineering
12+ years (PhD) of experience in pharmaceutical or biotechnology industry
Strong experience and technical mastery in LNP design & development including analytical characterization and CMC regulatory knowledge
Demonstrated expertise in developing liquid, frozen and lyophilized formulations of lipid-based nucleic acid formulations through clinical development
Prior experience leading and mentoring a team of >10 scientists/associates

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more orless than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paidand may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

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